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BMCBI
2007
13 years 7 months ago
2007
Background: Homology is a key concept in both evolutionary biology and genomics. Detection of homology is crucial in fields like the functional annotation of protein sequences and...
BMCBI
2008
13 years 7 months ago
2008
Background: Genome survey sequences (GSS) offer a preliminary global view of a genome since, unlike ESTs, they cover coding as well as non-coding DNA and include repetitive region...
BMCBI
2008
13 years 7 months ago
2008
Background: Comparative genomics is the analysis and comparison of genomes from different species. This area of research is driven by the large number of sequenced genomes and hea...
BMCBI
2008
13 years 7 months ago
2008
Background: MLPA method is a potentially useful semi-quantitative method to detect copy number alterations in targeted regions. In this paper, we propose a method for the normaliz...
BMCBI
2008
13 years 7 months ago
2008
Background: Confidence in pairwise alignments of biological sequences, obtained by various methods such as Blast or Smith-Waterman, is critical for automatic analyses of genomic d...