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» Dimensions of Component Based Development
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BMCBI
2010
191views more  BMCBI 2010»
13 years 8 months ago
Colonyzer: automated quantification of micro-organism growth characteristics on solid agar
Background: High-throughput screens comparing growth rates of arrays of distinct micro-organism cultures on solid agar are useful, rapid methods of quantifying genetic interaction...
Conor Lawless, Darren J. Wilkinson, Alexander Youn...
BMCBI
2010
92views more  BMCBI 2010»
13 years 8 months ago
Integrating gene expression and GO classification for PCA by preclustering
Background: Gene expression data can be analyzed by summarizing groups of individual gene expression profiles based on GO annotation information. The mean expression profile per g...
Jorn R. de Haan, Ester Piek, René C. van Sc...
BMCBI
2010
109views more  BMCBI 2010»
13 years 8 months ago
ParallABEL: an R library for generalized parallelization of genome-wide association studies
Background: Genome-Wide Association (GWA) analysis is a powerful method for identifying loci associated with complex traits and drug response. Parts of GWA analyses, especially th...
Unitsa Sangket, Surakameth Mahasirimongkol, Wasun ...
BMCBI
2010
170views more  BMCBI 2010»
13 years 8 months ago
Integrative analysis of gene expression and copy number alterations using canonical correlation analysis
Background: With the rapid development of new genetic measurement methods, several types of genetic alterations can be quantified in a high-throughput manner. While the initial fo...
Charlotte Soneson, Henrik Lilljebjörn, Thoas ...
BMCBI
2007
183views more  BMCBI 2007»
13 years 8 months ago
Considerations in the identification of functional RNA structural elements in genomic alignments
Background: Accurate identification of novel, functional noncoding (nc) RNA features in genome sequence has proven more difficult than for exons. Current algorithms identify and s...
Tomas Babak, Benjamin J. Blencowe, Timothy R. Hugh...