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BIOINFORMATICS
2008
172views more  BIOINFORMATICS 2008»
13 years 8 months ago
Fitting a geometric graph to a protein-protein interaction network
Motivation: Finding a good network null model for protein-protein interaction (PPI) networks is a fundamental issue. Such a model would provide insights into the interplay between...
Desmond J. Higham, Marija Rasajski, Natasa Przulj
BMCBI
2010
146views more  BMCBI 2010»
13 years 8 months ago
Nonnegative principal component analysis for mass spectral serum profiles and biomarker discovery
Background: As a novel cancer diagnostic paradigm, mass spectroscopic serum proteomic pattern diagnostics was reported superior to the conventional serologic cancer biomarkers. Ho...
Henry Han
EC
2007
160views ECommerce» more  EC 2007»
13 years 7 months ago
Agent-Based Model of Genotype Editing
Evolutionary algorithms rarely deal with ontogenetic, non-inherited alteration of genetic information because they are based on a direct genotype-phenotype mapping. In contrast, i...
Chien-Feng Huang, Jasleen Kaur, Ana Gabriela Magui...
JSAC
2006
105views more  JSAC 2006»
13 years 7 months ago
Network Topology Inference Based on End-to-End Measurements
Abstract--We consider using traceroute-like end-to-end measurement to infer the underlay topology for a group of hosts. One major issue is the measurement cost. Given hosts in an a...
Xing Jin, Wai-Pun Ken Yiu, S.-H. Gary Chan, Yajun ...
GPEM
2007
119views more  GPEM 2007»
13 years 7 months ago
Genomic mining for complex disease traits with "random chemistry"
Our rapidly growing knowledge regarding genetic variation in the human genome offers great potential for understanding the genetic etiology of disease. This, in turn, could revolut...
Margaret J. Eppstein, Joshua L. Payne, Bill C. Whi...