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RECOMB
2003
Springer
14 years 7 months ago
Modeling dependencies in protein-DNA binding sites
The availability of whole genome sequences and high-throughput genomic assays opens the door for in silico analysis of transcription regulation. This includes methods for discover...
Yoseph Barash, Gal Elidan, Nir Friedman, Tommy Kap...
CIBCB
2006
IEEE
14 years 1 months ago
A Systematic Computational Approach for Transcription Factor Target Gene Prediction
— Computational prediction of transcription factor’s binding sites and regulatory target genes has great value to the biological studies of cellular process. Existing practices...
Ji He, Xinbin Dai, Xuechun Zhao
BMCBI
2008
129views more  BMCBI 2008»
13 years 7 months ago
Motif-directed network component analysis for regulatory network inference
Background: Network Component Analysis (NCA) has shown its effectiveness in discovering regulators and inferring transcription factor activities (TFAs) when both microarray data a...
Chen Wang, Jianhua Xuan, Li Chen, Po Zhao, Yue Wan...
BMCBI
2006
129views more  BMCBI 2006»
13 years 7 months ago
BIPAD: A web server for modeling bipartite sequence elements
Background: Many dimeric protein complexes bind cooperatively to families of bipartite nucleic acid sequence elements, which consist of pairs of conserved half-site sequences sepa...
Chengpeng Bi, Peter K. Rogan
NN
2006
Springer
13 years 7 months ago
Self-organizing neural networks to support the discovery of DNA-binding motifs
Identification of the short DNA sequence motifs that serve as binding targets for transcription factors is an important challenge in bioinformatics. Unsupervised techniques from t...
Shaun Mahony, Panayiotis V. Benos, Terry J. Smith,...