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BMCBI
2010
147views more  BMCBI 2010»
13 years 7 months ago
baySeq: Empirical Bayesian methods for identifying differential expression in sequence count data
Background: High throughput sequencing has become an important technology for studying expression levels in many types of genomic, and particularly transcriptomic, data. One key w...
Thomas J. Hardcastle, Krystyna A. Kelly
BMCBI
2010
115views more  BMCBI 2010»
13 years 7 months ago
Non-coding RNA detection methods combined to improve usability, reproducibility and precision
Background: Non-coding RNAs gain more attention as their diverse roles in many cellular processes are discovered. At the same time, the need for efficient computational prediction...
Peter Raasch, Ulf Schmitz, Nadja Patenge, Julio Ve...
BMCBI
2004
131views more  BMCBI 2004»
13 years 7 months ago
Detection of chromosomal regions showing differential gene expression in human skeletal muscle and in alveolar rhabdomyosarcoma
Background: Rhabdomyosarcoma is a relatively common tumour of the soft tissue, probably due to regulatory disruption of growth and differentiation of skeletal muscle stem cells. I...
Andrea Bisognin, Stefania Bortoluzzi, Gian Antonio...
BMCBI
2007
148views more  BMCBI 2007»
13 years 7 months ago
WeederH: an algorithm for finding conserved regulatory motifs and regions in homologous sequences
Background: This work addresses the problem of detecting conserved transcription factor binding sites and in general regulatory regions through the analysis of sequences from homo...
Giulio Pavesi, Federico Zambelli, Graziano Pesole
BMCBI
2007
139views more  BMCBI 2007»
13 years 7 months ago
XSTREAM: A practical algorithm for identification and architecture modeling of tandem repeats in protein sequences
Background: Biological sequence repeats arranged in tandem patterns are widespread in DNA and proteins. While many software tools have been designed to detect DNA tandem repeats (...
Aaron M. Newman, James B. Cooper