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» Discovery of Regulatory Connections in Microarray Data
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BMCBI
2006
239views more  BMCBI 2006»
13 years 6 months ago
Applying dynamic Bayesian networks to perturbed gene expression data
Background: A central goal of molecular biology is to understand the regulatory mechanisms of gene transcription and protein synthesis. Because of their solid basis in statistics,...
Norbert Dojer, Anna Gambin, Andrzej Mizera, Bartek...
BMCBI
2007
112views more  BMCBI 2007»
13 years 6 months ago
Inferring biological functions and associated transcriptional regulators using gene set expression coherence analysis
Background: Gene clustering has been widely used to group genes with similar expression pattern in microarray data analysis. Subsequent enrichment analysis using predefined gene s...
Tae-Min Kim, Yeun-Jun Chung, Mun-Gan Rhyu, Myeong ...
JCST
2008
124views more  JCST 2008»
13 years 6 months ago
Clustering by Pattern Similarity
The task of clustering is to identify classes of similar objects among a set of objects. The definition of similarity varies from one clustering model to another. However, in most ...
Haixun Wang, Jian Pei
BMCBI
2007
174views more  BMCBI 2007»
13 years 7 months ago
Inferring activity changes of transcription factors by binding association with sorted expression profiles
Background: The identification of transcription factors (TFs) associated with a biological process is fundamental to understanding its regulatory mechanisms. From microarray data,...
Chao Cheng, Xiting Yan, Fengzhu Sun, Lei M. Li
BMCBI
2008
124views more  BMCBI 2008»
13 years 7 months ago
Literature-aided meta-analysis of microarray data: a compendium study on muscle development and disease
Background: Comparative analysis of expression microarray studies is difficult due to the large influence of technical factors on experimental outcome. Still, the identified diffe...
Rob Jelier, Peter A. C. 't Hoen, Ellen Sterrenburg...