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143
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BMCBI
2008
15 years 2 months ago
2008
Background: The most common substitution matrices currently used (BLOSUM and PAM) are based on protein sequences with average amino acid distributions, thus they do not represent ...
126
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BMCBI
2007
15 years 2 months ago
2007
Background: Traditional HTML interfaces for input to and output from Bioinformatics analysis on the Web are highly variable in style, content and data formats. Combining multiple ...
127
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BMCBI
2010
15 years 2 months ago
2010
Background: High-throughput sequencing (HTS) technologies play important roles in the life sciences by allowing the rapid parallel sequencing of very large numbers of relatively s...
121
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BMCBI
2008
15 years 2 months ago
2008
Background: Large biological data sets, such as expression profiles, benefit from reduction of random noise. Principal component (PC) analysis has been used for this purpose, but ...
148
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BMCBI
2007
15 years 2 months ago
2007
Background: We present a probabilistic topic-based model for content similarity called pmra that underlies the related article search feature in PubMed. Whether or not a document ...