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BMCBI
2004
131views more  BMCBI 2004»
13 years 7 months ago
Detection of chromosomal regions showing differential gene expression in human skeletal muscle and in alveolar rhabdomyosarcoma
Background: Rhabdomyosarcoma is a relatively common tumour of the soft tissue, probably due to regulatory disruption of growth and differentiation of skeletal muscle stem cells. I...
Andrea Bisognin, Stefania Bortoluzzi, Gian Antonio...
BMCBI
2004
130views more  BMCBI 2004»
13 years 7 months ago
PATTERNFINDER: combined analysis of DNA regulatory sequences and double-helix stability
Background: Regulatory regions that function in DNA replication and gene transcription contain specific sequences that bind proteins as well as less-specific sequences in which th...
Yanlin Huang, David Kowalski
BMCBI
2004
125views more  BMCBI 2004»
13 years 7 months ago
A functional hierarchical organization of the protein sequence space
Background: It is a major challenge of computational biology to provide a comprehensive functional classification of all known proteins. Most existing methods seek recurrent patte...
Noam Kaplan, Moriah Friedlich, Menachem Fromer, Mi...
BMCBI
2004
111views more  BMCBI 2004»
13 years 7 months ago
Multiclass discovery in array data
Background: A routine goal in the analysis of microarray data is to identify genes with expression levels that correlate with known classes of experiments. In a growing number of ...
Yingchun Liu, Markus Ringnér
BMCBI
2004
112views more  BMCBI 2004»
13 years 7 months ago
SPOC: A widely distributed domain associated with cancer, apoptosis and transcription
Background: The Split ends (Spen) family are large proteins characterised by N-terminal RNA recognition motifs (RRMs) and a conserved SPOC (Spen paralog and ortholog C-terminal) d...
Luis Sánchez-Pulido, Ana María Rojas...
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