Background: The occurrence of a genetic bottleneck in HIV sexual or mother-to-infant transmission has been well documented. This results in a majority of new infections being homo...
Elena E. Giorgi, Bob Funkhouser, Gayathri Athreya,...
Background: Evolutionary analysis provides a formal framework for comparative analysis of genomic and other data. In evolutionary analysis, observed data are treated as the termin...
Thomas Hladish, Vivek Gopalan, Chengzhi Liang, Wei...
Background: Information resources on the World Wide Web play an indispensable role in modern biology. But integrating data from multiple sources is often encumbered by the need to...
J. Christopher Bare, Paul T. Shannon, Amy K. Schmi...
Background: Orthology is one of the cornerstones of gene function prediction. Dividing the phylogenetic relations between genes into either orthologs or paralogs is however an ove...
Background: Kernel-based classification and regression methods have been successfully applied to modelling a wide variety of biological data. The Kernel-based Orthogonal Projectio...