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BMCBI
2007
13 years 10 months ago
2007
Background: An indirect approach is usually used to estimate the metabolic fluxes of an organism: couple the available measurements with known biological constraints (e.g. stoichi...
BMCBI
2007
13 years 10 months ago
2007
Background: Proteins are the primary regulatory agents of transcription even though mRNA expression data alone, from systems like DNA microarrays, are widely used. In addition, th...
BMCBI
2008
13 years 10 months ago
2008
Background: In the present investigation, we have used an exhaustive metabolite profiling approach to search for biomarkers in recombinant Aspergillus nidulans (mutants that produ...
BMCBI
2007
13 years 10 months ago
2007
Background: The combination of mass spectrometry and solution phase amide hydrogen/deuterium exchange (H/D exchange) experiments is an effective method for characterizing protein ...
BMCBI
2010
13 years 10 months ago
2010
Background: Microevolution is the study of short-term changes of alleles within a population and their effects on the phenotype of organisms. The result of the below-species-level...