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BMCBI
2007
169views more  BMCBI 2007»
13 years 9 months ago
Transcriptional regulatory network refinement and quantification through kinetic modeling, gene expression microarray data and i
Background: Gene expression microarray and other multiplex data hold promise for addressing the challenges of cellular complexity, refined diagnoses and the discovery of well-targ...
Abdallah Sayyed-Ahmad, Kagan Tuncay, Peter J. Orto...
BMCBI
2007
140views more  BMCBI 2007»
13 years 9 months ago
Investigations into the relationship between feedback loops and functional importance of a signal transduction network based on
Background: A number of studies on biological networks have been carried out to unravel the topological characteristics that can explain the functional importance of network nodes...
Yung-Keun Kwon, Sun Shim Choi, Kwang-Hyun Cho
BMCBI
2008
86views more  BMCBI 2008»
13 years 9 months ago
Piecewise multivariate modelling of sequential metabolic profiling data
Background: Modelling the time-related behaviour of biological systems is essential for understanding their dynamic responses to perturbations. In metabolic profiling studies, the...
Mattias Rantalainen, Olivier Cloarec, Timothy M. D...
BMCBI
2008
150views more  BMCBI 2008»
13 years 8 months ago
13C labeling experiments at metabolic nonstationary conditions: An exploratory study
Background: Stimulus Response Experiments to unravel the regulatory properties of metabolic networks are becoming more and more popular. However, their ability to determine enzyme...
Sebastian Aljoscha Wahl, Katharina Nöh, Wolfg...
CORR
2008
Springer
92views Education» more  CORR 2008»
13 years 8 months ago
Accelerating Large-scale Data Exploration through Data Diffusion
Data-intensive applications often require exploratory analysis of large datasets. If analysis is performed on distributed resources, data locality can be crucial to high throughpu...
Ioan Raicu, Yong Zhao, Ian T. Foster, Alexander S....