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» Dynamics of gene expression in an artificial genome
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BIOINFORMATICS
2008
203views more  BIOINFORMATICS 2008»
13 years 7 months ago
The SGN comparative map viewer
Background: A common approach to understanding the genetic basis of complex traits is through identification of associated quantitative trait loci (QTL). Fine mapping QTLs require...
Lukas A. Mueller, Adri A. Mills, Beth Skwarecki, R...
BMCBI
2005
178views more  BMCBI 2005»
13 years 7 months ago
A quantization method based on threshold optimization for microarray short time series
Background: Reconstructing regulatory networks from gene expression profiles is a challenging problem of functional genomics. In microarray studies the number of samples is often ...
Barbara Di Camillo, Fatima Sanchez-Cabo, Gianna To...
BMCBI
2007
103views more  BMCBI 2007»
13 years 7 months ago
eQTL Viewer: visualizing how sequence variation affects genome-wide transcription
Background: Expression Quantitative Trait Locus (eQTL) mapping methods have been used to identify the genetic basis of gene expression variations. To map eQTL, thousands of expres...
Wei Zou, David L. Aylor, Zhao-Bang Zeng
BMCBI
2011
12 years 11 months ago
SeqGene: a comprehensive software solution for mining exome- and transcriptome- sequencing data
Background: The popularity of massively parallel exome and transcriptome sequencing projects demands new data mining tools with a comprehensive set of features to support a wide r...
Xutao Deng
GECCO
1999
Springer
130views Optimization» more  GECCO 1999»
13 years 12 months ago
Heterochrony and Adaptation in Developing Neural Networks
This paper discusses the simulation results of a model of biological development for neural networks based on a regulatory genome. The model’s results are analyzed using the fra...
Angelo Cangelosi