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BMCBI
2007
149views more  BMCBI 2007»
13 years 7 months ago
Robust imputation method for missing values in microarray data
Background: When analyzing microarray gene expression data, missing values are often encountered. Most multivariate statistical methods proposed for microarray data analysis canno...
Dankyu Yoon, Eun-Kyung Lee, Taesung Park
BIOINFORMATICS
2006
120views more  BIOINFORMATICS 2006»
13 years 7 months ago
Comparison of Affymetrix GeneChip expression measures
Motivation: In the Affymetrix GeneChip system, preprocessing occurs before one obtains expression level measurements. Because the number of competing preprocessing methods was lar...
Rafael A. Irizarry, Zhijin Wu, Harris A. Jaffee
BMCBI
2006
158views more  BMCBI 2006»
13 years 7 months ago
Parallelization of multicategory support vector machines (PMC-SVM) for classifying microarray data
Background: Multicategory Support Vector Machines (MC-SVM) are powerful classification systems with excellent performance in a variety of data classification problems. Since the p...
Chaoyang Zhang, Peng Li, Arun Rajendran, Youping D...
BMCBI
2005
114views more  BMCBI 2005»
13 years 7 months ago
Signal transduction pathway profiling of individual tumor samples
Background: Signal transduction pathways convey information from the outside of the cell to transcription factors, which in turn regulate gene expression. Our objective is to anal...
Thomas Breslin, Morten Krogh, Carsten Peterson, Ca...
BMCBI
2010
214views more  BMCBI 2010»
13 years 7 months ago
AutoSOME: a clustering method for identifying gene expression modules without prior knowledge of cluster number
Background: Clustering the information content of large high-dimensional gene expression datasets has widespread application in "omics" biology. Unfortunately, the under...
Aaron M. Newman, James B. Cooper