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BMCBI
2006
171views more  BMCBI 2006»
13 years 7 months ago
The effect of oligonucleotide microarray data pre-processing on the analysis of patient-cohort studies
Background: Intensity values measured by Affymetrix microarrays have to be both normalized, to be able to compare different microarrays by removing non-biological variation, and s...
Roel G. W. Verhaak, Frank J. T. Staal, Peter J. M....
JCB
2002
160views more  JCB 2002»
13 years 7 months ago
Inference from Clustering with Application to Gene-Expression Microarrays
There are many algorithms to cluster sample data points based on nearness or a similarity measure. Often the implication is that points in different clusters come from different u...
Edward R. Dougherty, Junior Barrera, Marcel Brun, ...
BMCBI
2007
143views more  BMCBI 2007»
13 years 7 months ago
Gene selection for classification of microarray data based on the Bayes error
Background: With DNA microarray data, selecting a compact subset of discriminative genes from thousands of genes is a critical step for accurate classification of phenotypes for, ...
Ji-Gang Zhang, Hong-Wen Deng
BMCBI
2007
123views more  BMCBI 2007»
13 years 7 months ago
Normalization and experimental design for ChIP-chip data
Background: Chromatin immunoprecipitation on tiling arrays (ChIP-chip) has been widely used to investigate the DNA binding sites for a variety of proteins on a genome-wide scale. ...
Shouyong Peng, Artyom A. Alekseyenko, Erica Larsch...
BIBE
2004
IEEE
107views Bioinformatics» more  BIBE 2004»
13 years 11 months ago
Enhanced pClustering and Its Applications to Gene Expression Data
Clustering has been one of the most popular methods to discover useful biological insights from DNA microarray. An interesting paradigm is simultaneous clustering of both genes an...
Sungroh Yoon, Christine Nardini, Luca Benini, Giov...