Discriminating between secreted and membrane proteins is a challenging task. This is particularly true for discriminating between transmembrane segments and signal peptides because...
Background: The signal peptide plays an important role in protein targeting and protein translocation in both prokaryotic and eukaryotic cells. This transient, short peptide seque...
The OrthoMCL database (http://orthomcl.cbil.upenn. edu) houses ortholog group predictions for 55 spe10 cies, including 16 bacterial and 4 archaeal genomes representing phylogeneti...
Feng Chen, Aaron J. Mackey, Christian J. Stoeckert...
Abstract. Protein fold recognition is an important step towards understanding protein three-dimensional structures and their functions. A conditional graphical model, i.e. segmenta...
Yan Liu, Jaime G. Carbonell, Peter Weigele, Vanath...
Motivation: Mapping of remote evolutionary links is a classic computational problem of much interest. Relating protein families allows for functional and structural inference on u...