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BMCBI
2008
174views more  BMCBI 2008»
13 years 7 months ago
Evolutionary approaches for the reverse-engineering of gene regulatory networks: A study on a biologically realistic dataset
Background: Inferring gene regulatory networks from data requires the development of algorithms devoted to structure extraction. When only static data are available, gene interact...
Cédric Auliac, Vincent Frouin, Xavier Gidro...
BMCBI
2010
110views more  BMCBI 2010»
13 years 7 months ago
GenHtr: a tool for comparative assessment of genetic heterogeneity in microbial genomes generated by massive short-read sequenci
Background: Microevolution is the study of short-term changes of alleles within a population and their effects on the phenotype of organisms. The result of the below-species-level...
GongXin Yu
BMCBI
2007
173views more  BMCBI 2007»
13 years 7 months ago
Predicting state transitions in the transcriptome and metabolome using a linear dynamical system model
Background: Modelling of time series data should not be an approximation of input data profiles, but rather be able to detect and evaluate dynamical changes in the time series dat...
Ryoko Morioka, Shigehiko Kanaya, Masami Y. Hirai, ...
BMCBI
2007
141views more  BMCBI 2007»
13 years 7 months ago
HeliCis: a DNA motif discovery tool for colocalized motif pairs with periodic spacing
Background: Correct temporal and spatial gene expression during metazoan development relies on combinatorial interactions between different transcription factors. As a consequence...
Erik Larsson, Per Lindahl, Petter Mostad
BMCBI
2008
186views more  BMCBI 2008»
13 years 7 months ago
Variable selection for large p small n regression models with incomplete data: Mapping QTL with epistases
Background: Identifying quantitative trait loci (QTL) for both additive and epistatic effects raises the statistical issue of selecting variables from a large number of candidates...
Min Zhang, Dabao Zhang, Martin T. Wells
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