The error threshold of replication is an important notion of the quasispecies evolution model; it is a critical mutation rate (error rate) beyond which structures obtained by an e...
Niching is an important technique for multimodal optimization. Most existing niching methods require specification of certain niching parameters in order to perform well. These nic...
Background: Structure prediction of membrane proteins is still a challenging computational problem. Hidden Markov models (HMM) have been successfully applied to the problem of pre...
Piero Fariselli, Pier Luigi Martelli, Rita Casadio
If-conversion is a compiler technique that reduces the misprediction penalties caused by hard-to-predict branches, transforming control dependencies into data dependencies. Althou...
Background: Quasi-steady state approximation (QSSA) based on time-scale analysis is known to be an effective method for simplifying metabolic reaction system, but the conventional...
Junwon Choi, Kyung-won Yang, Tai-yong Lee, Sang Yu...