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BIBM
2008
IEEE
14 years 1 months ago
2008
IEEE
Abstract—The exact relationship between protein active centers and protein functions is unclear even after decades of intensive study. To improve the functional prediction abilit...
BMCBI
2008
13 years 7 months ago
2008
Background: Amino acids responsible for structure, core function or specificity may be inferred from multiple protein sequence alignments where a limited set of residue types are ...
TCBB
2008
13 years 7 months ago
2008
Abstract-- Many statistical measures and algorithmic techniques have been proposed for studying residue coupling in protein families. Generally speaking, two residue positions are ...
BMCBI
2007
13 years 7 months ago
2007
Background: Proteins that evolve from a common ancestor can change functionality over time, and it is important to be able identify residues that cause this change. In this paper ...
BMCBI
2008
13 years 7 months ago
2008
Background: Identifying the active site of an enzyme is a crucial step in functional studies. While protein sequences and structures can be experimentally characterized, determini...