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BMCBI
2011
12 years 11 months ago
PRIN, a predicted rice interactome network
Background: Protein-protein interactions play a fundamental role in elucidating the molecular mechanisms of biomolecular function, signal transductions and metabolic pathways of l...
Haibin Gu, Pengcheng Zhu, Yinming Jiao, Yijun Meng...
JAMIA
2011
94views more  JAMIA 2011»
12 years 10 months ago
Protein-network modeling of prostate cancer gene signatures reveals essential pathways in disease recurrence
Objective Uncovering the dominant molecular deregulation among the multitude of pathways implicated in aggressive prostate cancer is essential to intelligently developing targeted...
James L. Chen, Jianrong Li, Walter M. Stadler, Yve...
BMCBI
2010
118views more  BMCBI 2010»
13 years 7 months ago
Identifying differentially regulated subnetworks from phosphoproteomic data
Background: Various high throughput methods are available for detecting regulations at the level of transcription, translation or posttranslation (e.g. phosphorylation). Integrati...
Martin Klammer, Klaus Godl, Andreas Tebbe, Christo...
ALMOB
2006
109views more  ALMOB 2006»
13 years 7 months ago
A novel functional module detection algorithm for protein-protein interaction networks
Background: The sparse connectivity of protein-protein interaction data sets makes identification of functional modules challenging. The purpose of this study is to critically eva...
Woochang Hwang, Young-Rae Cho, Aidong Zhang, Mural...
BMCBI
2010
160views more  BMCBI 2010»
13 years 7 months ago
Identification of functional hubs and modules by converting interactome networks into hierarchical ordering of proteins
Background: Protein-protein interactions play a key role in biological processes of proteins within a cell. Recent high-throughput techniques have generated protein-protein intera...
Young-Rae Cho, Aidong Zhang