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PAMI
2011
13 years 2 months ago
Approximately Global Optimization for Robust Alignment of Generalized Shapes
—In this paper, we introduce a novel method to solve shape alignment problems. We use gray-scale “images” to represent source shapes, and propose a novel two-component Gaussi...
Hongsheng Li, Tian Shen, Xiaolei Huang
BMCBI
2008
114views more  BMCBI 2008»
13 years 7 months ago
Testing the Coulomb/Accessible Surface Area solvent model for protein stability, ligand binding, and protein design
Background: Protein structure prediction and computational protein design require efficient yet sufficiently accurate descriptions of aqueous solvent. We continue to evaluate the ...
Marcel Schmidt am Busch, Anne Lopes, Najette Amara...
BMCBI
2004
156views more  BMCBI 2004»
13 years 7 months ago
DIALIGN P: Fast pair-wise and multiple sequence alignment using parallel processors
Background: Parallel computing is frequently used to speed up computationally expensive tasks in Bioinformatics. Results: Herein, a parallel version of the multi-alignment program...
Martin Schmollinger, Kay Nieselt, Michael Kaufmann...
RECOMB
2009
Springer
14 years 8 months ago
An Online Approach for Mining Collective Behaviors from Molecular Dynamics Simulations
Collective behavior involving distally separate regions in a protein is known to widely affect its function. In this paper, we present an online approach to study and characterize ...
Arvind Ramanathan, Pratul K. Agarwal, Maria Kurnik...
IOR
2006
177views more  IOR 2006»
13 years 7 months ago
Combinatorial Benders' Cuts for Mixed-Integer Linear Programming
Mixed-Integer Programs (MIP's) involving logical implications modelled through big-M coefficients, are notoriously among the hardest to solve. In this paper we propose and an...
Gianni Codato, Matteo Fischetti