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BMCBI
2004
88views more  BMCBI 2004»
13 years 9 months ago
Coronavirus 3CLpro proteinase cleavage sites: Possible relevance to SARS virus pathology
Background: Despite the passing of more than a year since the first outbreak of Severe Acute Respiratory Syndrome (SARS), efficient counter-measures are still few and many believe...
Lars Kiemer, Ole Lund, Søren Brunak, Nikola...
BMCBI
2004
111views more  BMCBI 2004»
13 years 9 months ago
Multiclass discovery in array data
Background: A routine goal in the analysis of microarray data is to identify genes with expression levels that correlate with known classes of experiments. In a growing number of ...
Yingchun Liu, Markus Ringnér
BMCBI
2004
96views more  BMCBI 2004»
13 years 9 months ago
Identification of regions in multiple sequence alignments thermodynamically suitable for targeting by consensus oligonucleotides
Background: Computer programs for the generation of multiple sequence alignments such as "Clustal W" allow detection of regions that are most conserved among many sequen...
Olga V. Matveeva, Brian T. Foley, Vladimir A. Nemt...
BMCBI
2004
151views more  BMCBI 2004»
13 years 9 months ago
Design, implementation and evaluation of a practical pseudoknot folding algorithm based on thermodynamics
Background: The general problem of RNA secondary structure prediction under the widely used thermodynamic model is known to be NP-complete when the structures considered include a...
Jens Reeder, Robert Giegerich
CGF
2004
133views more  CGF 2004»
13 years 9 months ago
SMARTPAPER: An Interactive and User Friendly Sketching System
This paper describes an interactive sketching system for 3D design/modeling that diverts from the conventional menu and button interfaces of CAD tools. The system, dubbed SMARTPAP...
Amit Shesh, Baoquan Chen
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