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BMCBI
2007
95views more  BMCBI 2007»
13 years 9 months ago
Phylogenetic tree information aids supervised learning for predicting protein-protein interaction based on distance matrices
Background: Protein-protein interactions are critical for cellular functions. Recently developed computational approaches for predicting protein-protein interactions utilize co-ev...
Roger A. Craig, Li Liao
BMCBI
2008
141views more  BMCBI 2008»
13 years 9 months ago
The development of PIPA: an integrated and automated pipeline for genome-wide protein function annotation
Background: Automated protein function prediction methods are needed to keep pace with high-throughput sequencing. With the existence of many programs and databases for inferring ...
Chenggang Yu, Nela Zavaljevski, Valmik Desai, Seth...
BMCBI
2008
202views more  BMCBI 2008»
13 years 9 months ago
Network motif-based identification of transcription factor-target gene relationships by integrating multi-source biological data
Background: Integrating data from multiple global assays and curated databases is essential to understand the spatiotemporal interactions within cells. Different experiments measu...
Yuji Zhang, Jianhua Xuan, Benildo de los Reyes, Ro...
BMCBI
2008
121views more  BMCBI 2008»
13 years 9 months ago
OntoDas - a tool for facilitating the construction of complex queries to the Gene Ontology
Background: Ontologies such as the Gene Ontology can enable the construction of complex queries over biological information in a conceptual way, however existing systems to do thi...
Kieran O'Neill, Alexander García Castro, An...
BMCBI
2010
151views more  BMCBI 2010»
13 years 9 months ago
Data reduction for spectral clustering to analyze high throughput flow cytometry data
Background: Recent biological discoveries have shown that clustering large datasets is essential for better understanding biology in many areas. Spectral clustering in particular ...
Habil Zare, Parisa Shooshtari, Arvind Gupta, Ryan ...