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    BMCBI
    2010
    174views more  BMCBI 2010»
    The effect of prior assumptions over the weights in BayesPI with application to study protein-DNA interactions from ChIP-based h
    13 years 8 months ago
    The effect of prior assumptions over the weights in BayesPI with application to study protein-DNA interactions from ChIP-based h
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    Background: To further understand the implementation of hyperparameters re-estimation technique in Bayesian hierarchical model, we added two more prior assumptions over the weight...
    Junbai Wang
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    BMCBI
    2010
    151views more  BMCBI 2010»
    CCRaVAT and QuTie - enabling analysis of rare variants in large-scale case control and quantitative trait association studies
    13 years 8 months ago
    CCRaVAT and QuTie - enabling analysis of rare variants in large-scale case control and quantitative trait association studies
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    Background: Genome-wide association studies have been successful in finding common variants influencing common traits. However, these associations only account for a fraction of t...
    Robert Lawrence, Aaron G. Day-Williams, Katherine ...
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    BMCBI
    2008
    242views more  BMCBI 2008»
    New time-scale criteria for model simplification of bio-reaction systems
    13 years 8 months ago
    New time-scale criteria for model simplification of bio-reaction systems
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    Background: Quasi-steady state approximation (QSSA) based on time-scale analysis is known to be an effective method for simplifying metabolic reaction system, but the conventional...
    Junwon Choi, Kyung-won Yang, Tai-yong Lee, Sang Yu...
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    BMCBI
    2007
    157views more  BMCBI 2007»
    A hybrid multiscale Monte Carlo algorithm (HyMSMC) to cope with disparity in time scales and species populations in intracellula
    13 years 8 months ago
    A hybrid multiscale Monte Carlo algorithm (HyMSMC) to cope with disparity in time scales and species populations in intracellula
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    Background: The fundamental role that intrinsic stochasticity plays in cellular functions has been shown via numerous computational and experimental studies. In the face of such e...
    Asawari Samant, Babatunde A. Ogunnaike, Dionisios ...
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    BMCBI
    2008
    186views more  BMCBI 2008»
    Variable selection for large p small n regression models with incomplete data: Mapping QTL with epistases
    13 years 8 months ago
    Variable selection for large p small n regression models with incomplete data: Mapping QTL with epistases
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    Background: Identifying quantitative trait loci (QTL) for both additive and epistatic effects raises the statistical issue of selecting variables from a large number of candidates...
    Min Zhang, Dabao Zhang, Martin T. Wells
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