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» Empirical Bayes analysis of single nucleotide polymorphisms
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BMCBI
2007
133views more  BMCBI 2007»
13 years 7 months ago
GenMAPP 2: new features and resources for pathway analysis
Background: Microarray technologies have evolved rapidly, enabling biologists to quantify genome-wide levels of gene expression, alternative splicing, and sequence variations for ...
Nathan Salomonis, Kristina Hanspers, Alexander C. ...
BMCBI
2006
95views more  BMCBI 2006»
13 years 7 months ago
Estimate haplotype frequencies in pedigrees
Background: Haplotype analysis has gained increasing attention in the context of association studies of disease genes and drug responsivities over the last years. The potential us...
Qiangfeng Zhang, YuZhong Zhao, Guoliang Chen, Yun ...
BMCBI
2007
95views more  BMCBI 2007»
13 years 7 months ago
ZPS: visualization of recent adaptive evolution of proteins
Background: Detection of adaptive amino acid changes in proteins under recent short-term selection is of great interest for researchers studying microevolutionary processes in mic...
Sujay Chattopadhyay, Daniel E. Dykhuizen, Evgeni V...
KDD
2008
ACM
181views Data Mining» more  KDD 2008»
14 years 7 months ago
Fastanova: an efficient algorithm for genome-wide association study
Studying the association between quantitative phenotype (such as height or weight) and single nucleotide polymorphisms (SNPs) is an important problem in biology. To understand und...
Xiang Zhang, Fei Zou, Wei Wang 0010
BMCBI
2010
89views more  BMCBI 2010»
13 years 7 months ago
Spatial normalization improves the quality of genotype calling for Affymetrix SNP 6.0 arrays
Background: Microarray measurements are susceptible to a variety of experimental artifacts, some of which give rise to systematic biases that are spatially dependent in a unique w...
High-Seng Chai, Terry M. Therneau, Kent R. Bailey,...