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114
Voted
BMCBI
2006
137views more  BMCBI 2006»
15 years 3 months ago
A maximum likelihood framework for protein design
Background: The aim of protein design is to predict amino-acid sequences compatible with a given target structure. Traditionally envisioned as a purely thermodynamic question, thi...
Claudia L. Kleinman, Nicolas Rodrigue, Céci...
149
Voted
BMCBI
2006
132views more  BMCBI 2006»
15 years 3 months ago
Genome-wide DNA polymorphism analyses using VariScan
Background: DNA sequence polymorphisms analysis can provide valuable information on the evolutionary forces shaping nucleotide variation, and provides an insight into the function...
Stephan Hutter, Albert J. Vilella, Julio Rozas
137
Voted
CAD
2006
Springer
15 years 3 months ago
An efficient, error-bounded approximation algorithm for simulating quasi-statics of complex linkages
Design and analysis of articulated mechanical structures, commonly referred to as linkages, is an integral part of any CAD/CAM system. The most common approaches formulate the pro...
Stephane Redon, Ming C. Lin
153
Voted
CGF
2006
202views more  CGF 2006»
15 years 3 months ago
GPU-based Collision Detection for Deformable Parameterized Surfaces
Based on the potential of current programmable GPUs, recently several approaches were developed that use the GPU to calculate deformations of surfaces like the folding of cloth or...
Alexander Greß, Michael Guthe, Reinhard Klei...
138
Voted
BMCBI
2007
104views more  BMCBI 2007»
15 years 3 months ago
Using contextual and lexical features to restructure and validate the classification of biomedical concepts
Background: Biomedical ontologies are critical for integration of data from diverse sources and for use by knowledge-based biomedical applications, especially natural language pro...
Jung-Wei Fan, Hua Xu, Carol Friedman