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BMCBI
2006
103views more  BMCBI 2006»
13 years 7 months ago
Correction of scaling mismatches in oligonucleotide microarray data
Background: Gene expression microarray data is notoriously subject to high signal variability. Moreover, unavoidable variation in the concentration of transcripts applied to micro...
Martino Barenco, Jaroslav Stark, Daniel Brewer, Da...
NAR
2006
100views more  NAR 2006»
13 years 7 months ago
The LIFEdb database in 2006
LIFEdb (http://www.LIFEdb.de) integrates data from large-scale functional genomics assays and manual cDNA annotation with bioinformatics gene expression and protein analysis. New ...
Alexander Mehrle, Heiko Rosenfelder, Ingo Schupp, ...
BMCBI
2010
144views more  BMCBI 2010»
13 years 7 months ago
Super-sparse principal component analyses for high-throughput genomic data
Background: Principal component analysis (PCA) has gained popularity as a method for the analysis of highdimensional genomic data. However, it is often difficult to interpret the ...
Donghwan Lee, Woojoo Lee, Youngjo Lee, Yudi Pawita...
ALMOB
2007
111views more  ALMOB 2007»
13 years 7 months ago
Transcriptional regulatory network discovery via multiple method integration: application to e. coli K12
Motivation: Transcriptional regulatory network (TRN) discovery from one method (e.g. microarray analysis, gene ontology, phylogenic similarity) does not seem feasible due to lack ...
Jingjun Sun, Kagan Tuncay, Alaa Abi Haidar, Lisa E...
BMCBI
2008
138views more  BMCBI 2008»
13 years 7 months ago
Systematic identification of yeast cell cycle transcription factors using multiple data sources
Background: Eukaryotic cell cycle is a complex process and is precisely regulated at many levels. Many genes specific to the cell cycle are regulated transcriptionally and are exp...
Wei-Sheng Wu, Wen-Hsiung Li