Background: Functional annotation of proteins remains a challenging task. Currently the scientific literature serves as the main source for yet uncurated functional annotations, b...
Background: The identification of groups of co-regulated genes and their transcription factors, called transcriptional modules, has been a focus of many studies about biological s...
Ho-Joon Lee, Thomas Manke, Ricardo Bringas, Martin...
MicroRNAs (miRNAs) have recently been discovered as an important class of non-coding RNA genes that play a major role in regulating gene expression, providing a means to control th...
Background: Serial Analysis of Gene Expressions (SAGE) produces gene expression measurements on a discrete scale, due to the finite number of molecules in the sample. This means t...
Background: It is well known that most of the binding free energy of protein interaction is contributed by a few key hot spot residues. These residues are crucial for understandin...