12 search results - page 2 / 3 » Ensemble Machine Methods for DNA Binding |
DMIN
2008
13 years 9 months ago
2008
The knowledge discovery process encounters the difficulties to analyze large amount of data. Indeed, some theoretical problems related to high dimensional spaces then appear and de...
BIOINFORMATICS
2006
13 years 7 months ago
2006
Motivation: Over 50% of human genes contain CpG islands in their 5'-regions. Methylation patterns of CpG islands are involved in tissue-specific gene expression and regulatio...
BMCBI
2006
13 years 7 months ago
2006
Background: There has been an explosion in the number of single nucleotide polymorphisms (SNPs) within public databases. In this study we focused on non-synonymous protein coding ...
BMCBI
2008
13 years 7 months ago
2008
Background: In this paper, it is proposed an optimization approach for producing reduced alphabets for peptide classification, using a Genetic Algorithm. The classification task i...
BMCBI
2010
13 years 7 months ago
2010
Background: It is well known that most of the binding free energy of protein interaction is contributed by a few key hot spot residues. These residues are crucial for understandin...