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» Ensemble of Linear Models for Predicting Drug Properties
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BMCBI
2010
97views more  BMCBI 2010»
13 years 6 months ago
Kinome-wide interaction modelling using alignment-based and alignment-independent approaches for kinase description and linear a
Background: Protein kinases play crucial roles in cell growth, differentiation, and apoptosis. Abnormal function of protein kinases can lead to many serious diseases, such as canc...
Maris Lapinsh, Jarl E. S. Wikberg
AAAI
2011
12 years 6 months ago
Exploiting Phase Transition in Latent Networks for Clustering
In this paper, we model the pair-wise similarities of a set of documents as a weighted network with a single cutoff parameter. Such a network can be thought of an ensemble of unwe...
Vahed Qazvinian, Dragomir R. Radev
ICML
2008
IEEE
14 years 7 months ago
Detecting statistical interactions with additive groves of trees
Discovering additive structure is an important step towards understanding a complex multi-dimensional function because it allows the function to be expressed as the sum of lower-d...
Daria Sorokina, Rich Caruana, Mirek Riedewald, Dan...
BMCBI
2007
143views more  BMCBI 2007»
13 years 6 months ago
An adaptive bin framework search method for a beta-sheet protein homopolymer model
Background: The problem of protein structure prediction consists of predicting the functional or native structure of a protein given its linear sequence of amino acids. This probl...
Alena Shmygelska, Holger H. Hoos
BIBE
2004
IEEE
149views Bioinformatics» more  BIBE 2004»
13 years 10 months ago
Interactive 3D Protein Structure Visualization Using Virtual Reality
Large-scale biomedical data sets of macromolecular structures such as DNA and proteins describe highly complex biomolecular entities which often consist of thousands of atoms and ...
Elke Moritz, Jörg Meyer