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JCB
2002
131views more  JCB 2002»
13 years 7 months ago
Modeling and Simulation of Genetic Regulatory Systems: A Literature Review
In order to understand the functioning of organisms on the molecular level, we need to know which genes are expressed, when and where in the organism, and to which extent. The reg...
Hidde de Jong
TCBB
2008
137views more  TCBB 2008»
13 years 7 months ago
Toward Verified Biological Models
The last several decades have witnessed a vast accumulation of biological data and data analysis. Many of these data sets represent only a small fraction of the system's behav...
Avital Sadot, Jasmin Fisher, Dan Barak, Yishai Adm...
IEE
2008
120views more  IEE 2008»
13 years 7 months ago
Software evolutionary dynamics modelled as the activity of an actor-network
The pressures which act on a software system over its life from inception to retirement are many and varied. It is an important goal in considering software evolvability to unders...
Paul Wernick, Tracy Hall, Chrystopher L. Nehaniv
JIB
2007
95views more  JIB 2007»
13 years 7 months ago
Integration of constraints documented in SBML, SBO, and the SBML Manual facilitates validation of biological models
The creation of quantitative, simulatable, Systems Biology Markup Language (SBML) models that accurately simulate the system under study is a time-intensive manual process that re...
Allyson L. Lister, Matthew R. Pocock, Anil Wipat
ALIFE
2005
13 years 7 months ago
Evolution of DNA Uptake Signal Sequences
The DNA of some naturally competent species of bacteria contains a large number of evenly distributed copies of a short sequence. This highly overrepresented sequence is believed t...
Dominique Chu, Hoong-Chien Lee, Tom Lenaerts