With the increasing availability of experimental data on gene-gene and protein-protein interactions, modeling of gene regulatory networks has gained a special attention lately. To ...
Abhishek Garg, Ioannis Xenarios, Luis Mendoza, Gio...
Many years of experimental and computational molecular biology of model organisms such as Escherichia coli and Saccharomyces cerevisiae has elucidated the gene regulatory network i...
Background: Gene regulatory networks play essential roles in living organisms to control growth, keep internal metabolism running and respond to external environmental changes. Un...
Identifying gene regulatory networks from high-throughput gene expression data is one of the most important goals of bioinformatics, but it remains difficult to define what makes a...
Mechanistic models for transcriptional regulation are derived using the methods of equilibrium statistical mechanics, to model equilibrating processes that occur at a fast time sc...