Background: DNA microarrays, which determine the expression levels of tens of thousands of genes from a sample, are an important research tool. However, the volume of data they pr...
Alexander L. Richards, Peter Holmans, Michael C. O...
Background: Three-color microarray experiments can be performed to assess drug effects on the genomic scale. The methodology may be useful in shortening the cycle, reducing the co...
Background: Recent advances in antibody microarray technology have made it possible to measure the expression of hundreds of proteins simultaneously in a competitive dual-colour a...
Background: Success of metabolomics as the phenotyping platform largely depends on its ability to detect various sources of biological variability. Removal of platform-specific so...
Marko Sysi-Aho, Mikko Katajamaa, Laxman Yetukuri, ...
The permutation procedure is widely used to assess the significance level (p-value) of a test statistic. This approach is asymptotically consistent. In genomics and proteomics st...