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GECCO
2003
Springer
127views Optimization» more  GECCO 2003»
14 years 25 days ago
Complex Function Sets Improve Symbolic Discriminant Analysis of Microarray Data
Abstract. Our ability to simultaneously measure the expression levels of thousands of genes in biological samples is providing important new opportunities for improving the diagnos...
David M. Reif, Bill C. White, Nancy Olsen, Thomas ...
BMCBI
2008
134views more  BMCBI 2008»
13 years 7 months ago
Clustering cancer gene expression data: a comparative study
Background The use of clustering methods for the discovery of cancer subtypes has drawn a great deal of attention in the scientific community. While bioinformaticians have propose...
Marcílio Carlos Pereira de Souto, Ivan G. C...
BMCBI
2008
106views more  BMCBI 2008»
13 years 7 months ago
SpliceCenter: A suite of web-based bioinformatic applications for evaluating the impact of alternative splicing on RT-PCR, RNAi,
Background: Over 60% of protein-coding genes in vertebrates express mRNAs that undergo alternative splicing. The resulting collection of transcript isoforms poses significant chal...
Michael C. Ryan, Barry Zeeberg, Natasha J. Caplen,...
BMCBI
2008
190views more  BMCBI 2008»
13 years 7 months ago
Which missing value imputation method to use in expression profiles: a comparative study and two selection schemes
Background: Gene expression data frequently contain missing values, however, most downstream analyses for microarray experiments require complete data. In the literature many meth...
Guy N. Brock, John R. Shaffer, Richard E. Blakesle...
BMCBI
2007
173views more  BMCBI 2007»
13 years 7 months ago
Ringo - an R/Bioconductor package for analyzing ChIP-chip readouts
Background: Chromatin immunoprecipitation combined with DNA microarrays (ChIP-chip) is a high-throughput assay for DNA-protein-binding or post-translational chromatin/histone modi...
Joern Toedling, Oleg Sklyar, Tammo Krueger, Jenny ...