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» Evaluation Measures of Multiple Sequence Alignments
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BMCBI
2010
154views more  BMCBI 2010»
13 years 7 months ago
Fine-tuning structural RNA alignments in the twilight zone
Background: A widely used method to find conserved secondary structure in RNA is to first construct a multiple sequence alignment, and then fold the alignment, optimizing a score ...
Andreas Bremges, Stefanie Schirmer, Robert Giegeri...
NAR
2006
61views more  NAR 2006»
13 years 7 months ago
MAVL/StickWRLD: analyzing structural constraints using interpositional dependencies in biomolecular sequence alignments
The increasing availability of structurally aligned protein families has made it possible to use statistical methods to discover regions of interpositional dependenciesof residue ...
Hatice Gulcin Ozer, William C. Ray
BMCBI
2010
90views more  BMCBI 2010»
13 years 7 months ago
Local alignment of generalized k-base encoded DNA sequence
Background: DNA sequence comparison is a well-studied problem, in which two DNA sequences are compared using a weighted edit distance. Recent DNA sequencing technologies however o...
Nils Homer, Stanley F. Nelson, Barry Merriman
BMCBI
2011
12 years 11 months ago
Improving pan-genome annotation using whole genome multiple alignment
Background: Rapid annotation and comparisons of genomes from multiple isolates (pan-genomes) is becoming commonplace due to advances in sequencing technology. Genome annotations c...
Samuel V. Angiuoli, Julie C. Dunning Hotopp, Steve...
CF
2008
ACM
13 years 9 months ago
Cell-SWat: modeling and scheduling wavefront computations on the cell broadband engine
This paper contributes and evaluates a model and a methodology for implementing parallel wavefront algorithms on the Cell Broadband Engine. Wavefront algorithms are vital in sever...
Ashwin M. Aji, Wu-chun Feng, Filip Blagojevic, Dim...