Reverse-engineering of gene networks using linear models often results in an underdetermined system because of excessive unknown parameters. In addition, the practical utility of ...
Background: Microarray data is frequently used to characterize the expression profile of a whole genome and to compare the characteristics of that genome under several conditions....
Fabrice Berger, Bertrand De Meulder, Anthoula Gaig...
The ultimate goal of data mining is to extract knowledge from massive data. Knowledge is ideally represented as human-comprehensible patterns from which end-users can gain intuiti...
Background: Independently derived expression profiles of the same biological condition often have few genes in common. In this study, we created populations of expression profiles...
Michael Gormley, William Dampier, Adam Ertel, Bilg...
Background: ChIP-chip data, which indicate binding of transcription factors (TFs) to DNA regions in vivo, are widely used to reconstruct transcriptional regulatory networks. Howev...