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BMCBI
2007
134views more  BMCBI 2007»
13 years 6 months ago
Nearest Neighbor Networks: clustering expression data based on gene neighborhoods
Background: The availability of microarrays measuring thousands of genes simultaneously across hundreds of biological conditions represents an opportunity to understand both indiv...
Curtis Huttenhower, Avi I. Flamholz, Jessica N. La...
BMCBI
2008
135views more  BMCBI 2008»
13 years 6 months ago
Knowledge-guided multi-scale independent component analysis for biomarker identification
Background: Many statistical methods have been proposed to identify disease biomarkers from gene expression profiles. However, from gene expression profile data alone, statistical...
Li Chen, Jianhua Xuan, Chen Wang, Ie-Ming Shih, Yu...
BMCBI
2006
116views more  BMCBI 2006»
13 years 6 months ago
ROKU: a novel method for identification of tissue-specific genes
Background: One of the important goals of microarray research is the identification of genes whose expression is considerably higher or lower in some tissues than in others. We wo...
Koji Kadota, Jiazhen Ye, Yuji Nakai, Tohru Terada,...
BMCBI
2006
374views more  BMCBI 2006»
13 years 6 months ago
AMDA: an R package for the automated microarray data analysis
Background: Microarrays are routinely used to assess mRNA transcript levels on a genome-wide scale. Large amount of microarray datasets are now available in several databases, and...
Mattia Pelizzola, Norman Pavelka, Maria Foti, Paol...
BMCBI
2008
124views more  BMCBI 2008»
13 years 6 months ago
A probe-treatment-reference (PTR) model for the analysis of oligonucleotide expression microarrays
Background: Microarray pre-processing usually consists of normalization and summarization. Normalization aims to remove non-biological variations across different arrays. The norm...
Huanying Ge, Chao Cheng, Lei M. Li