Background: Clustering the information content of large high-dimensional gene expression datasets has widespread application in "omics" biology. Unfortunately, the under...
Background: The activity of proteins within the cell is characterized by their motions, flexibility, interactions or even the particularly intriguing case of partially unfolded st...
Background: Enzymes are responsible for the catalysis of the biochemical reactions in metabolic pathways. Analogous enzymes are able to catalyze the same reactions, but they prese...
A key problem in video content analysis using dynamic graphical models is to learn a suitable model structure given some observed visual data. We propose a Completed Likelihood AI...
Motivation Quantitative estimation of the regulatory relationship between transcription factors and genes is a fundamental stepping stone when trying to develop models of cellular...
Guido Sanguinetti, Neil D. Lawrence, Magnus Rattra...