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» Evolutionary Approaches to DNA Sequencing with Errors
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BMCBI
2008
179views more  BMCBI 2008»
13 years 11 months ago
Bayesian modeling of recombination events in bacterial populations
Background: We consider the discovery of recombinant segments jointly with their origins within multilocus DNA sequences from bacteria representing heterogeneous populations of fa...
Pekka Marttinen, Adam Baldwin, William P. Hanage, ...
BMCBI
2006
103views more  BMCBI 2006»
13 years 11 months ago
Cis-motifs upstream of the transcription and translation initiation sites are effectively revealed by their positional disequili
Background: The discovery of cis-regulatory motifs still remains a challenging task even though the number of sequenced genomes is constantly growing. Computational analyses using...
Kenneth W. Berendzen, Kurt Stüber, Klaus Hart...
BMCBI
2007
167views more  BMCBI 2007»
13 years 11 months ago
Applying negative rule mining to improve genome annotation
Background: Unsupervised annotation of proteins by software pipelines suffers from very high error rates. Spurious functional assignments are usually caused by unwarranted homolog...
Irena I. Artamonova, Goar Frishman, Dmitrij Frishm...
RECOMB
2002
Springer
14 years 11 months ago
String barcoding: uncovering optimal virus signatures
There are many critical situations when one needs to rapidly identify an unidentified pathogen from among a given set of previously sequenced pathogens. DNA or RNA hybridization c...
Sam Rash, Dan Gusfield
BMCBI
2005
132views more  BMCBI 2005»
13 years 10 months ago
CLPM: A Cross-Linked Peptide Mapping Algorithm for Mass Spectrometric Analysis
Background: Protein-protein, protein-DNA and protein-RNA interactions are of central importance in biological systems. Quadrapole Time-of-flight (Q-TOF) mass spectrometry is a sen...
Yong Tang, Yingfeng Chen, Cheryl F. Lichti, Roger ...