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» Evolutionary Robotics: A Review
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BMCBI
2008
126views more  BMCBI 2008»
13 years 10 months ago
c-REDUCE: Incorporating sequence conservation to detect motifs that correlate with expression
Background: Computational methods for characterizing novel transcription factor binding sites search for sequence patterns or "motifs" that appear repeatedly in genomic ...
Katerina Kechris, Hao Li
CORR
2010
Springer
125views Education» more  CORR 2010»
13 years 10 months ago
Critical control of a genetic algorithm
Based on speculations coming from statistical mechanics and the conjectured existence of critical states, I propose a simple heuristic in order to control the mutation probability...
Raphaël Cerf
BMCBI
2006
130views more  BMCBI 2006»
13 years 9 months ago
MicroTar: predicting microRNA targets from RNA duplexes
Background: The accurate prediction of a comprehensive set of messenger RNAs (targets) regulated by animal microRNAs (miRNAs) remains an open problem. In particular, the predictio...
Rahul Thadani, Martti T. Tammi
BMCBI
2006
117views more  BMCBI 2006»
13 years 9 months ago
Incorporating background frequency improves entropy-based residue conservation measures
Background: Several entropy-based methods have been developed for scoring sequence conservation in protein multiple sequence alignments. High scoring amino acid positions may corr...
Kai Wang, Ram Samudrala
BMCBI
2007
115views more  BMCBI 2007»
13 years 9 months ago
Local comparison of protein structures highlights cases of convergent evolution in analogous functional sites
Background: We performed an exhaustive search for local structural similarities in an ensemble of non-redundant protein functional sites. With the purpose of finding new examples ...
Gabriele Ausiello, Daniele Peluso, Allegra Via, Ma...