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» Evolutionary Two-Dimensional DNA Sequence Alignment
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BMCBI
2007
233views more  BMCBI 2007»
13 years 10 months ago
160-fold acceleration of the Smith-Waterman algorithm using a field programmable gate array (FPGA)
Background: To infer homology and subsequently gene function, the Smith-Waterman (SW) algorithm is used to find the optimal local alignment between two sequences. When searching s...
Isaac T. S. Li, Warren Shum, Kevin Truong
BMCBI
2011
13 years 1 months ago
Combinatorial analysis and algorithms for quasispecies reconstruction using next-generation sequencing
Background: Next-generation sequencing (NGS) offers a unique opportunity for high-throughput genomics and has potential to replace Sanger sequencing in many fields, including de-n...
Mattia C. F. Prosperi, Luciano Prosperi, Alessandr...
ICPP
2009
IEEE
14 years 4 months ago
Load Balance in the Phylogenetic Likelihood Kernel
—Recent advances in DNA sequencing techniques have led to an unprecedented accumulation and availability of molecular sequence data that needs to be analyzed. This data explosion...
Alexandros Stamatakis, Michael Ott
RECOMB
2002
Springer
14 years 10 months ago
Comparison of minisatellites
In the class of repeated sequences that occur in DNA, minisatellites have been found polymorphic and became useful tools in genetic mapping and forensic studies. They consist of a...
Eric Rivals, Sèverine Bérard
BMCBI
2006
103views more  BMCBI 2006»
13 years 9 months ago
Cis-motifs upstream of the transcription and translation initiation sites are effectively revealed by their positional disequili
Background: The discovery of cis-regulatory motifs still remains a challenging task even though the number of sequenced genomes is constantly growing. Computational analyses using...
Kenneth W. Berendzen, Kurt Stüber, Klaus Hart...