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GECCO
2006
Springer
165views Optimization» more  GECCO 2006»
13 years 11 months ago
Comparing mathematical models on the problem of network inference
In this paper we address the problem of finding gene regulatory networks from experimental DNA microarray data. We focus on the evaluation of the performance of different mathemat...
Christian Spieth, Nadine Hassis, Felix Streichert
GECCO
2008
Springer
179views Optimization» more  GECCO 2008»
13 years 8 months ago
Evolution of discrete gene regulatory models
Gene regulatory networks (GRNs) are complex control systems that govern the interaction of genes, which ultimately control cellular processes at the protein level. GRNs can be ted...
Afshin Esmaeili, Christian Jacob
BMCBI
2007
130views more  BMCBI 2007»
13 years 7 months ago
A model-based optimization framework for the inference of regulatory interactions using time-course DNA microarray expression da
Background: Proteins are the primary regulatory agents of transcription even though mRNA expression data alone, from systems like DNA microarrays, are widely used. In addition, th...
Reuben Thomas, Carlos J. Paredes, Sanjay Mehrotra,...
BIOCOMP
2006
13 years 9 months ago
Theoretical Bounds for the Number of Inferable Edges in Sparse Random Networks
Abstract-- The inference of a network structure from experimental data providing dynamical information about the underlying system of investigation is an important and still outsta...
Frank Emmert-Streib, Matthias Dehmer
ATVA
2008
Springer
131views Hardware» more  ATVA 2008»
13 years 9 months ago
Computation Tree Regular Logic for Genetic Regulatory Networks
Model checking has proven to be a useful analysis technique not only for concurrent systems, but also for the genetic regulatory networks (Grns) that govern the functioning of livi...
Radu Mateescu, Pedro T. Monteiro, Estelle Dumas, H...