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BMCBI
2010
156views more  BMCBI 2010»
13 years 8 months ago
Mathematical model for empirically optimizing large scale production of soluble protein domains
Background: Efficient dissection of large proteins into their structural domains is critical for high throughput proteome analysis. So far, no study has focused on mathematically ...
Eisuke Chikayama, Atsushi Kurotani, Takanori Tanak...
BIOINFORMATICS
2011
13 years 9 days ago
ProDy: Protein Dynamics Inferred from Theory and Experiments
Summary: We developed a Python package, ProDy, for structurebased analysis of protein dynamics. ProDy allows for quantitative characterization of structural variations in heteroge...
Ahmet Bakan, Lidio M. Meireles, Ivet Bahar
BMCBI
2005
162views more  BMCBI 2005»
13 years 8 months ago
Accelerated probabilistic inference of RNA structure evolution
Background: Pairwise stochastic context-free grammars (Pair SCFGs) are powerful tools for evolutionary analysis of RNA, including simultaneous RNA sequence alignment and secondary...
Ian Holmes
BMCBI
2008
97views more  BMCBI 2008»
13 years 8 months ago
SODa: An Mn/Fe superoxide dismutase prediction and design server
Background: Superoxide dismutases (SODs) are ubiquitous metalloenzymes that play an important role in the defense of aerobic organisms against oxidative stress, by converting reac...
Jean Marc Kwasigroch, René Wintjens, Dimitr...
BMCBI
2010
141views more  BMCBI 2010»
13 years 8 months ago
BioPhysConnectoR: Connecting Sequence Information and Biophysical Models
Background: One of the most challenging aspects of biomolecular systems is the understanding of the coevolution in and among the molecule(s). A complete, theoretical picture of th...
Franziska Hoffgaard, Philipp Weil, Kay Hamacher