146 search results - page 4 / 30 » Evolutionary design of the energy function for protein struc... |
ISMB
1996
13 years 8 months ago
1996
The native conformation of a protein, in a given environment, is determined entirely by the various interatomic interactions dictated by the amino acid sequence (1-3). We describe...
BMCBI
2008
13 years 7 months ago
2008
Background: Non-homology based methods such as phylogenetic profiles are effective for predicting functional relationships between proteins with no considerable sequence or struct...
BMCBI
2010
13 years 7 months ago
2010
Background: Knowledge-based potentials have been widely used in the last 20 years for fold recognition, protein structure prediction from amino acid sequence, ligand binding, prot...
GECCO
2003
Springer
14 years 20 days ago
2003
Springer
We have developed an evolutionary approach for the flexible docking that is now an important component of a rational drug design. This automatic docking tool, referred to as the G...
BMCBI
2006
13 years 7 months ago
2006
Background: Protein sequence alignment is one of the basic tools in bioinformatics. Correct alignments are required for a range of tasks including the derivation of phylogenetic t...