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BMCBI
2010
128views more  BMCBI 2010»
13 years 9 months ago
VIGOR, an annotation program for small viral genomes
Background: The decrease in cost for sequencing and improvement in technologies has made it easier and more common for the re-sequencing of large genomes as well as parallel seque...
Shiliang Wang, Jaideep P. Sundaram, David Spiro
BMCBI
2008
128views more  BMCBI 2008»
13 years 9 months ago
Pairwise covariance adds little to secondary structure prediction but improves the prediction of non-canonical local structure
Background: Amino acid sequence probability distributions, or profiles, have been used successfully to predict secondary structure and local structure in proteins. Profile models ...
Christopher Bystroff, Bobbie-Jo M. Webb-Robertson
BMCBI
2007
121views more  BMCBI 2007»
13 years 9 months ago
Predicting zinc binding at the proteome level
Background: Metalloproteins are proteins capable of binding one or more metal ions, which may be required for their biological function, for regulation of their activities or for ...
Andrea Passerini, Claudia Andreini, Sauro Menchett...
BMCBI
2007
87views more  BMCBI 2007»
13 years 9 months ago
'Unite and conquer': enhanced prediction of protein subcellular localization by integrating multiple specialized tools
Background: Knowing the subcellular location of proteins provides clues to their function as well as the interconnectivity of biological processes. Dozens of tools are available f...
Yao Qing Shen, Gertraud Burger
BMCBI
2007
157views more  BMCBI 2007»
13 years 9 months ago
A hybrid multiscale Monte Carlo algorithm (HyMSMC) to cope with disparity in time scales and species populations in intracellula
Background: The fundamental role that intrinsic stochasticity plays in cellular functions has been shown via numerous computational and experimental studies. In the face of such e...
Asawari Samant, Babatunde A. Ogunnaike, Dionisios ...