Background: Post-translational modification by Small Ubiquitin-like Modifiers (SUMO) has been implicated in protein targeting, in the maintenance of genomic integrity and in trans...
Maria Novatchkova, Andreas Bachmair, Birgit Eisenh...
— Automatic protein structure predictors use the notion of energy to guide the search towards good candidate structures. The energy functions used by the state-of-the-art predict...
Pawel Widera, Jonathan M. Garibaldi, Natalio Krasn...
Background: Protein remote homology detection is a central problem in computational biology. Most recent methods train support vector machines to discriminate between related and ...
Background: Proteins that evolve from a common ancestor can change functionality over time, and it is important to be able identify residues that cause this change. In this paper ...
Understanding the protein folding mechanism remains a grand challenge in structural biology. In the past several years, computational theories in molecular dynamics have been empl...