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BMCBI
2007
139views more  BMCBI 2007»
13 years 8 months ago
XSTREAM: A practical algorithm for identification and architecture modeling of tandem repeats in protein sequences
Background: Biological sequence repeats arranged in tandem patterns are widespread in DNA and proteins. While many software tools have been designed to detect DNA tandem repeats (...
Aaron M. Newman, James B. Cooper
GECCO
2007
Springer
192views Optimization» more  GECCO 2007»
14 years 2 months ago
SDR: a better trigger for adaptive variance scaling in normal EDAs
Recently, advances have been made in continuous, normal– distribution–based Estimation–of–Distribution Algorithms (EDAs) by scaling the variance up from the maximum–like...
Peter A. N. Bosman, Jörn Grahl, Franz Rothlau...
BMCBI
2010
104views more  BMCBI 2010»
13 years 8 months ago
Parameters for accurate genome alignment
Background: Genome sequence alignments form the basis of much research. Genome alignment depends on various mundane but critical choices, such as how to mask repeats and which sco...
Martin C. Frith, Michiaki Hamada, Paul Horton
BMCBI
2007
179views more  BMCBI 2007»
13 years 8 months ago
rMotifGen: random motif generator for DNA and protein sequences
Background: Detection of short, subtle conserved motif regions within a set of related DNA or amino acid sequences can lead to discoveries about important regulatory domains such ...
Eric C. Rouchka, C. Timothy Hardin
BMCBI
2005
158views more  BMCBI 2005»
13 years 8 months ago
Automated generation of heuristics for biological sequence comparison
Background: Exhaustive methods of sequence alignment are accurate but slow, whereas heuristic approaches run quickly, but their complexity makes them more difficult to implement. ...
Guy St. C. Slater, Ewan Birney