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BMCBI
2007
13 years 7 months ago
2007
Background: Remote homology detection is a challenging problem in Bioinformatics. Arguably, profile Hidden Markov Models (pHMMs) are one of the most successful approaches in addre...
ISMIS
2005
Springer
14 years 15 days ago
2005
Springer
In this paper, we adapt a statistical learning approach, inspired by automated topic segmentation techniques in speech-recognized documents to the challenging protein segmentation ...
ISMB
2004
13 years 8 months ago
2004
Motivation: Non-coding RNAs (ncRNAs)--functional RNA molecules not coding for proteins--are grouped into hundreds of families of homologs. To find new members of an ncRNA gene fam...
NAR
2007
13 years 6 months ago
2007
The SUPERFAMILY database provides protein domain assignments, at the SCOP ‘superfamily’ level, for the predicted protein sequences in over 400 completed genomes. A superfamily...
JCB
2007
13 years 7 months ago
2007
Analysis of biopolymer sequences and structures generally adopts one of two approaches: use of detailed biophysical theoretical models of the system with experimentally-determined...