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BMCBI
2007
117views more  BMCBI 2007»
13 years 8 months ago
Supervised multivariate analysis of sequence groups to identify specificity determining residues
Background: Proteins that evolve from a common ancestor can change functionality over time, and it is important to be able identify residues that cause this change. In this paper ...
Iain M. Wallace, Desmond G. Higgins
BMCBI
2007
154views more  BMCBI 2007»
13 years 8 months ago
Bounds on the distribution of the number of gaps when circles and lines are covered by fragments: Theory and practical applicati
Background: The question of how a circle or line segment becomes covered when random arcs are marked off has arisen repeatedly in bioinformatics. The number of uncovered gaps is o...
John Moriarty, Julian R. Marchesi, Anthony Metcalf...
BMCBI
2008
173views more  BMCBI 2008»
13 years 8 months ago
Gene Vector Analysis (Geneva): A unified method to detect differentially-regulated gene sets and similar microarray experiments
Background: Microarray experiments measure changes in the expression of thousands of genes. The resulting lists of genes with changes in expression are then searched for biologica...
Stephen W. Tanner, Pankaj Agarwal
BMCBI
2008
208views more  BMCBI 2008»
13 years 8 months ago
GraphFind: enhancing graph searching by low support data mining techniques
Background: Biomedical and chemical databases are large and rapidly growing in size. Graphs naturally model such kinds of data. To fully exploit the wealth of information in these...
Alfredo Ferro, Rosalba Giugno, Misael Mongiov&igra...
CORR
2010
Springer
111views Education» more  CORR 2010»
13 years 8 months ago
Improved complexity bounds for real root isolation using Continued Fractions
We consider the problem of isolating the real roots of a square-free polynomial with integer coefficients using (variants of) the continued fraction algorithm (CF). We introduce a...
Elias P. Tsigaridas
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