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BMCBI
2007
133views more  BMCBI 2007»
13 years 10 months ago
AGGRESCAN: a server for the prediction and evaluation of "hot spots" of aggregation in polypeptides
Background: Protein aggregation correlates with the development of several debilitating human disorders of growing incidence, such as Alzheimer's and Parkinson's disease...
Oscar Conchillo-Solé, Natalia S. de Groot, ...
BMCBI
2007
239views more  BMCBI 2007»
13 years 10 months ago
Pre-processing Agilent microarray data
Background: Pre-processing methods for two-sample long oligonucleotide arrays, specifically the Agilent technology, have not been extensively studied. The goal of this study is to...
Marianna Zahurak, Giovanni Parmigiani, Wayne Yu, R...
BMCBI
2008
160views more  BMCBI 2008»
13 years 10 months ago
Feature selection environment for genomic applications
Background: Feature selection is a pattern recognition approach to choose important variables according to some criteria in order to distinguish or explain certain phenomena (i.e....
Fabrício Martins Lopes, David Correa Martin...
BMCBI
2008
119views more  BMCBI 2008»
13 years 10 months ago
A new method for 2D gel spot alignment: application to the analysis of large sample sets in clinical proteomics
Background: In current comparative proteomics studies, the large number of images generated by 2D gels is currently compared using spot matching algorithms. Unfortunately, differe...
Sabine Pérès, Laurence Molina, Nicol...
BMCBI
2006
184views more  BMCBI 2006»
13 years 10 months ago
PathSys: integrating molecular interaction graphs for systems biology
Background: The goal of information integration in systems biology is to combine information from a number of databases and data sets, which are obtained from both high and low th...
Michael Baitaluk, Xufei Qian, Shubhada Godbole, Al...