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BMCBI
2010
13 years 10 months ago
2010
Background: PDZ domains mediate protein-protein interactions involved in important biological processes through the recognition of short linear motifs in their target proteins. Tw...
BMCBI
2006
13 years 10 months ago
2006
Background: Local structures of target mRNAs play a significant role in determining the efficacies of antisense oligonucleotides (ODNs), but some structure-based target site selec...
BMCBI
2006
13 years 10 months ago
2006
Background: More and more disordered regions have been discovered in protein sequences, and many of them are found to be functionally significant. Previous studies reveal that dis...
BMCBI
2007
13 years 10 months ago
2007
High-throughput methods can directly detect the set of interacting proteins in yeast but the results are often incomplete and exhibit high false positive and false negative rates....
TCBB
2010
13 years 8 months ago
2010
—The correct interpretation of many molecular biology experiments depends in an essential way on the accuracy and consistency of the existing annotation databases. Such databases...